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1. 1976 Keen, C. L. and Hurley, L. S. Copper supplementation
in quaking mutant mice: 2. 1977 Keen, C. L. and Hurley, L. S. Zinc absorption through skin: correction of zinc deficiency in the rat. American Journal of Clinical Nutrition 30: 528 530. 3. 1977 Rucker, R. B., Yau, M. C., Keen, C. L., Mohanram, M. and Riemann, W. G. Acid soluble protein synthesis in aorta: effects of dietary cholesterol, elevated levels of vitamin D 3, cyclic 3', 5', adenosine monophosphate (cAMP) and effectors of cAMP metabolism. Artery 3: 368 378. 4. 1977 Theriault, L. L., Dungan, D. C., Simons, S., Keen, C. L. and Hurley, L. S. Lipid and myelin abnormalities of brain in the crinkled mouse. Proceedings of the Society for Experimental Biology and Medicine 155: 549 553. 5. 1979 deRosa, G., Duncan, D. S., Keen, C. L. and Hurley, L. S. Evaluation of negative staining technique for determination of CN insensitive superoxide dismutase activity. Biochimica and Biophysica Acta 566: 32 39. 6. 1979 Keen, C. L. The relationship of the mutant genes quaking and crinkled in mice to copper metabolism. Ph.D. Dissertation. University of California, Davis. 7. 1979 Keen, C.L. and Hurley, L.S. Superoxide dismutase activity in the crinkled mutant mouse: Ameliorative effects of dietary copper supplementation. Proceedings of the Society for Experimental Biology and Medicine 162: 152 156. 8. 1979 Keen, C. L. and Hurley, L. S. Developmental patterns of copper and zinc concentrations In mouse liver and brain: Evidence that the gene crinkled (cr) is associated with an abnormality in copper metabolism. Journal of Inorganic Biochemistry 11: 269 277. 9. 1979 Lönnerdal, B., Keen, C. L. and Hurley, L. S. Isoelectric focusing of superoxide dismutase isoenzymes. Federation of European Biochemical Societies Letters 108: 51 55. 10. 1979 Hurley, L. S. and Keen, C. L. Teratogenic effects of copper. In: Copper in the Environment Part 2: Health Effects. (J. Nriagu, ed.), John Wiley and Sons, Inc., New York, 33 56. 11. 1980 Lönnerdal, B., Keen, C. L., Fransson, G. B., Hambraeus, L. and Hurley, L. S. New perspectives on iron supplementation of milk. Journal of Pediatrics 96:242. 12. 1980 Keen, C. L., Lönnerdal, B., Sloan, M. V. and Hurley, L. S. Effect of dietary iron, copper, and zinc chelates of nitrilotriacetic acid (NTA) on trace metal concentrations in rat milk and maternal and pup tissues. The Journal of Nutrition 110: 897 906. 13. 1980 DeRosa, G., Keen, C. L., Leach, R. M. and Hurley, L. S. Regulation of superoxide dismutase activity by dietary manganese. The Journal of Nutrition 110: 795 804. 14. 1980 Keen, C. L., Lönnerdal, B., Sloan, M. V. and Hurley, L. S. Effects of milking procedure on rat milk composition. Physiology and Behavior 24: 613 615. 15. 1980 Lönnerdal, B., Keen, C. L., Hoffman, B. and Hurley, L. S. Copper ligands in human milk. A vehicle for copper supplementation in the treatment of Menkes' disease? American Journal of Diseases of Children 134: 802 803. 16. 1980 Keen, C. L., Saltman, P. and Hurley, L. S. Copper nitrilotriacetate: a potent therapeutic agent in the treatment of a genetic disorder of copper metabolism. American Journal of Clinical Nutrition 33: 1789 1800. 17. 1980 Indrieri, R. J., Holliday, T. A. and Keen, C. L. Critical evaluation of creatinine phosphokinase in cerebrospinal fluid of dogs with neurologic disease. American Journal of Veterinary Research 41: 1299 1303. 18. 1980 Lönnerdal, B., Schneeman, B. 0., Keen, C. L. and Hurley, L. S. Molecular distribution of zinc in biliary and pancreatic secretions. Biological Trace Element Research 2: 149 158. 19. 1980 Keen, C. L. and Hurley, L. S. Developmental changes in concentrations of iron, copper, and zinc in mouse tissues. Mechanisms of Ageing and Development 13: 161 176. 20. 1980 Hurley, L. S., Keen, C. L. and Lönnerdal, B. Copper in fetal and neonatal development. In: The Biological Roles of Copper. CIBA Foundation Symposium, London, England, March 1980. Excerpta Medica pp. 227 245. 21. 1980 Lönnerdal, B., Clegg, M., Keen, C. L. and Hurley, L. S. Effects of wet ashing techniques on the determination of trace element concentrations in biological samples. In: Trace Element Analytical Chemistry in Medicine and Biology (P. Bratter and P. Schramel, eds.), Proceedings of First International Workshop, Neuherberg, Federal Republic of Germany, April 1980, Walter de Gruyter, New York, 1980, pp. 619 629. 22. 1980 Keen, C. L., Lönnerdal, B., Stein, T. W. and Hurley, L. S. Superoxide dismutase isoenzymes in bovine and human milk. Biological Trace Element Research 2: 221 227. 23. 1980 Lönnerdal, B., Keen, C. L., Sloan, M. V. and Hurley, L. S. Molecular localization of zinc in rat milk and neonatal intestine. The Journal of Nutrition 110: 2414 2419. 24. 1981 Keen, C. L., Lönnerdal, B. and Fisher, G. L. Seasonal variations and the effects of age on serum copper and zinc values in the dog. American Journal of Veterinary Research 42: 347 350. 25. 1981 Keen, C. L., Lönnerdal, B., Clegg, M. and Hurley, L. S. Developmental changes in composition of rat milk: Trace elements, minerals, protein, carbohydrate, and fat. The Journal of Nutrition 111: 226 236. 26. 1981 Keen, C. L., Lönnerdal, B. and Fisher, G. L. Age related variations in hepatic iron, copper, zinc and selenium concentrations in Beagles. American Journal of Veterinary Research 42: 1884 1887. 27. 1981 Lönnerdal, B., Keen, C. L., Hurley, L. S. and Fisher, G. L. Developmental changes in the composition of Beagle dog milk. American Journal of Veterinary Research 42: 662 666. 28. 1981 Lönnerdal, B., Keen, C. L. and Hurley, L. S. Iron, copper, zinc and manganese in milk. Annual Reviews of Nutrition 1: 149 174. 29. 1981 Feldman, B. F., Keen, C. L., Kaneko, J. J. and Farber, T. B. Anemia of inflammatory disease in the dog: measurement of hepatic superoxide dismutase, hepatic nonheme iron, copper, zinc, and ceruloplasmin and serum iron, copper and zinc. American Journal of Veterinary Research 42: 1114 1117. 30. 1981 Feldman, B. F., Keen, C. L., Kaneko, J. J. and Farver, T. B. Anemia of inflammatory disease in the dog: measurement of hepatic superoxide dismutase, hepatic nonheme, copper, zinc, and ceruloplasmins and serum iron, copper, and zinc. (Letter) American Journal of Veterinary Research 42: 1844. 31. 1981 Clegg, M. S., Keen, C. L., Lönnerdal, B. and Hurley, L. S. Influence of ashing techniques on the analysis of trace elements in animal samples. I: Wet ashing. Biological Trace Element Research 3: 107 115. 32. 1981 Clegg, M. S., Keen, C. L., Lönnerdal, B. and Hurley, L. S. Influence of ashing technique on the analysis of trace elements in biological samples. II: Dry ashing. Biological Trace Element Research 3: 237 244. 33. 1981 Hurley, L. S., Keen, C. L., Lönnerdal, B., Mark Savage, P. and Hackman, R. Trace elements, genetic factors, and drugs in developmental abnormalities. In: Trace Element Metabolism in Man and Animals (TEMA 4) (J. McC. Howell, J. M. Gawthorne and C. L. White eds.), Griffin Press Limited, Netly, South Australia, 283 286. 34. 1981 Lönnerdal, B., Keen, C. L. and Hurley, L. S. Trace elements in milk from various species. In: Trace Element Metabolism in Man and Animals (TEMA 4) (J. McC. Howell, J. M. Gawthorne and C. L. White eds.), Griffin Press Limited, Netly, South Australia, 249 252. 35. 1981 Keen, C. L., Lönnerdal, B. and Hurley, L. S. Developmental changes in zinc and copper in mouse and rat tissues. In: Trace Element Metabolism in Man and Animals (TEMA 4) (J. McC. Howell, J. M. Gawthorne and C. L. White eds.), Griffin Press Limited, Netly, South Australia, 287 290. 36. 1982 Shrader, R. E., Keen, C. L., Hurley, L. S. and Zeman, F. J. Hematologic and trace element alterations following chronic maternal ingestion of propylthiourea. Journal of Experimental Hematology 10: 44 55. 37. 1982 Stein, T. N., Keen, C. L., Lönnerdal, B. and Hurley, L. S. Effect of sample preparation on analysis of superoxide dismutase activity and isoenzymes. Journal of Inorganic Biochemistry 16: 71 77. 38. 1982 Hurley, L. S., Gordon, P., Keen, C. L. and Merkhofer, L. Circadian variation in rat plasma zinc and rapid effect of dietary zinc deficiency. Proceedings for the Society of Experimental Biology and Medicine 170: 48 52. 39. 1982 Lönnerdal, B., Keen, C. L. and Hurley, L. S. Increases of iron in maternal milk and tissues of the suckling rat by supplementation with FeNTA. In: The Biochemistry and Physiology of Iron (P. Saltman and J. Hegenauer eds.), Elsevier Science Publishing Co., Inc., New York, 231 232. 40. 1982 Keen, C. L., Lönnerdal, B. and Hurley, L. S. Comparative aspects of postnatal changes in iron metabolism. In: The Biochemistry and Physiology of Iron (P. Saltman and J. Hegenauer eds.), Elsevier Science Publishing Co., Inc., New York, 603 604. 41. 1982 Keen, C. L., Lönnerdal, B. and Hurley, L. S. Increased milk iron by dietary supplementation entirely beneficial? American Journal of Clinical Nutrition. (Letter) 35: 627 628. 42. 1982 Dressendorfer, R. H., Wade, C. E., Keen, C. L. and Scaff, J. H. Plasma mineral levels in marathon runners during a 20 day road race. Journal of Sports Medicine 10: 113 118. 43. 1982 Keen, C. L., Lönnerdal, B. and Hurley L. S. Teratogenic effects of copper deficiency and excess. In: Inflammatory Diseases of Copper (J. R. J. Sorenson, ed.) Humana Press, Clifton, New Jersey, 109 121. 44. 1982 Keen, C. L., Lönnerdal, B., Clegg, M. S., Hurley, L. S., Morris, J. G., Rogers, Q. R. and Rucker, R. B. Developmental changes in composition of cats' milk: Trace elements, minerals, protein, carbohydrate and fat. The Journal of Nutrition 112: 1763 1769. 45. 1982 Keen, C. L., Feldman, B. F., Knight, J., O'Neill, S., Ferrell, F. and Hurley, L. S. The influence of high concentrations of dietary copper on vitamin K dependent coagulation factors. Proceedings for Society of Experimental Biology and Medicine 170: 471 475. 46. 1982 Keen, C. L., Cohen, N. L., Lönnerdal, R. and Hurley, L. S. Low tissue copper and teratogenesis in Trientine treated rats. Lancet i: 1127. 47. 1982 Clegg, M. S., Keen, C. L., Lönnerdal, B., and Hurley, L. S. Analysis of trace elements in animal tissues. III. Determination of manganese by graphite furnace atomic absorption spectrophotometry. Biological Trace Element Research 4: 145 156. 48. 1982 Keen, C. L., Mark Savage, P., Lönnerdal, B. and Hurley, L. S. Teratogenesis and low copper status resulting from D penicillamine in rats. Teratology 26: 163 165. 49. 1982 Hurley, L. S., Keen, C. L. and Lönnerdal, B. Trace elements and teratology: an interactional perspective. In: Genetic Toxicology: An Agricultural Perspective (R. A. Fleck and A. Hollander, eds.), pp. 189 199. 50. 1982 Lönnerdal, B., Keen, C. L. and Hurley, L. S. Zinc in milk: concentration and distribution. In: Clinical Applications of Recent Advances in Zinc Metabolism (A Prasad, B. Hetzel and I. Dreosti, Eds.), Alan R. Liss, Inc., New York, pp. 79 87. 51. 1982 Keen, C. L., Lönnerdal, B. and Hurley, L. S. Increased milk iron by dietary supplementation entirely beneficial? Reply to Celada. American Journal of Clinical Nutrition (Letter) 36: 967 968. 52. 1982 Lönnerdal, B. and Keen, C. L. Metal chelate affinity chromatography of proteins. Journal of Applied Biochemistry 4: 203 208. 53. 1983 Lönnerdal, B. and Keen, C. L. Trace element absorption in infants: potential and limitations. In: Reproductive and Developmental Toxicity of Metals (T. W. Clarkson, G. F. Nordberg and P. R. Sanger, Eds.), Plenum Press, New York. pp. 759 776. 54. 1983 Keen, C. L., Mark Savage, P., Lönnerdal, B. and Hurley, L. S. Teratogenic effects of D penicillamine in rats: Relation to copper deficiency. Drug Nutrient Interactions 2: 17 34. 55. 1983 Lönnerdal, B., Keen, C. L., Ohtake, M. and T. Tamura. Iron, zinc, copper, and manganese in infant formulas. American Journal of Diseases of Children 137: 433 437. 56. 1983 Mark Savage, P., Keen, C. L. and Hurley, L. S. Reduction by copper supplementation of teratogenic effects of D penicillamine. The Journal of Nutrition 113: 501 510. 57. 1983 Zidenberg Cherr, S., Keen, C. L., Lönnerdal, B. and Hurley, L. S. Dietary superoxide dismutase does not affect tissue levels. American Journal of Clinical Nutrition 37: 5 7. 58. 1983 Hurley, L. S., Keen, C. L. and Lönnerdal, B. Aspects of trace element interactions during development. Federation Proceedings 42: 1735 1739. 59. 1983 Masters, D. G., Keen, C. L., L÷nnerdal, B. and Hurley, L. S. Zinc deficiency teratogenicity: The protective role of maternal tissue catabolism. The Journal of Nutrition 113: 905 912. 60. 1983 Schneeman, B. 0., Lönnerdal, B., Keen, C. L. and Hurley, L. S. Zinc and copper in rat bile and pancreatic fluid: effects of surgery. The Journal of Nutrition 113: 1165 1168. 61. 1983 Dubick, M. A. and Keen, C. L. Tissue trace elements and lung superoxide dismutase activity in mice exposed to ozone. Toxicology Letters 17: 355 360. 62. 1983 Masters, D. G., Keen, C. L., Lönnerdal, B. and Hurley, L. S. Comparative aspects of dietary copper and zinc deficiencies in pregnant rats. The Journal of Nutrition 113: 1448 1451. 63. 1983 Sandstrom, B., Keen, C. L. and Lönnerdal, B. An experimental model for studies of zinc bioavailability from milk and infant formulas using extrinsic labelling. American Journal of Clinical Nutrition 38: 420 428. 64. 1983 Keen, C. L., Cohen, N. L., Lönnerdal, B. and Hurley, L. S. Teratogenesis and low copper status resulting from triethylenetetramine in rats. Proceedings of the Society for Experimental Biology and Medicine 173: 598 605. 65. 1983 Hurley, L. S., Dungan, D. D., Keen, C. L. and Lönnerdal, B. The effects of vitamin E on zinc deficiency teratogenesis in rats. The Journal of Nutrition 113: 1875 1877. 66. 1983 Keen, C. L., Clegg, M. S., Lönnerdal, B. and Hurley, L. S. Whole blood manganese as an indicator of body manganese status. New England Journal of Medicine 308: 1230. 67. 1983 Cohen, N. L., Keen, C. L., Lönnerdal, B. and Hurley, L. S. The effect of copper chelating drugs on liver iron mobilization in the adult rat. Biochemical and Biophysical Research Communications 113: 127 134. 68. 1983 Keen, C. L., Lönnerdal, B. and Hurley, L. S. Drug induced copper deficiency: A model for copper deficiency teratogenicity. Teratology 28: 155 156. 69. 1983 Keen, C. L., Mutch, P. B., Lönnerdal, B., Amemiya, K. and Hurley, L. S. Effect of zinc supplementation on magnesium deficiency during pregnancy in rats. Magnesium 2: 113 119. 70. 1983 Fransson, G. B., Keen, C. L. and Lönnerdal, B. Supplementation of milk with iron bound to lactoferrin using weanling rats. I. Effects on hematology and tissue iron. Journal of Pediatric Gastroenterology and Nutrition 2: 693 700. 71. 1983 Zidenberg Cherr, S., Keen, C. L., Lönnerdal, B. and Hurley, L. S. Superoxide dismutase activity and lipid peroxidation: Developmental correlations affected by manganese deficiency. The Journal of Nutrition 113: 2498 2504. 72. 1983 Doong, G., Keen, C. L., Rogers, Q., Morris, J. and Rucker, R. B. Selected features of copper metabolism in the cat. The Journal of Nutrition 113: 1963 1971. 73. 1983 Cohen, N. L., Keen, C. L., Lönnerdal, B. and Hurley, L. S. The effect of copper supplementation on the teratogenic effects of triethylenetetramine. Drug Nutrient Interactions 2: 203 210. 74. 1984 Branum, J. E., Keen, C. L., Ling, G. V. and Franti, C. E. Selected Physical and chemical characteristics of prostatic fluid collected by ejaculation from healthy dogs and dogs with bacterial prostatitis. American Journal of Veterinary Research 45: 825 829. 75. 1984 Keen, C. L., Fransson, G. B. and Lönnerdal, B. Supplementation of milk with iron bound to lactoferrin using weanling mice. II. Effects on tissue manganese, zinc and copper. Journal of Pediatric Gastroenterology and Nutrition 3: 256 261. 76. 1984 Lönnerdal, B., Smith C. and Keen, C. L. Analysis of breast milk current methodologies and future needs. Journal of Gastroenterology and Nutrition 3: 290 295. 77. 1984 Keen, C. L., Cohen, N. L., Hurley, L. S. and Lönnerdal, B. Molecular localization of copper and zinc in rat fetal liver in dietary and drug induced copper deficiency. Biochemical and Biophysical Research Communications 118: 697 703. 78. 1984 Golub, M. S., Keen, C. L., Vijayan, V. K., Gershwin, M. E. and Hurley, L. S. Early development of brain and behavior in mice fed a marginally zinc deficient diet. In: The Neurobiology of Zinc. Part B: Deficiency, Toxicity and Pathology (C. Fredrickson, ed.), Alan R. Liss, New York, NY, pp. 65 75. 79. 1984 Hurley, L. S., Keen, C. L. and Baly, D. Manganese deficiency and toxicity: effects on carbohydrate metabolism in the rat. Neurotoxicology 5: 97 104. 80. 1984 Reinstein, N. H., Lönnerdal, B., Keen, C. L. and Hurley, L. S. Zinc copper interactions in the pregnant rat. Fetal outcome and maternal and fetal zinc, copper and iron. The Journal of Nutrition 114: 1266 1279. 81. 1984 Kwock, R. 0., Keen, C. L., Hegenauer, J., Saltman, P., Hurley, L. S. and Lönnerdal, B. Retention and distribution of iron added to cow's milk and human milk as various salts and chelates. The Journal of Nutrition 114: 1454 1461. 82. 1984 Lönnerdal, B., Keen, C. L. and Sandstrom, B. Zinc bioavailability from infant foods. Reply to Craig. American Journal of Clinical Nutrition (Letter) 39: 982 983. 83. 1984 Baly, D. L., Curry, D. L., Keen, C. L. and Hurley, L. S. Effect of manganese deficiency on insulin secretion and carbohydrate homeostasis in rats. The Journal of Nutrition 114: 1438 1446. 84. 1984 Lönnerdal, B., Keen, C. L., Glazier, C. E. and Anderson, J. A longitudinal study of Rhesus monkey (Macaca mulatta) milk composition: Trace elements, minerals, protein, carbohydrate and fat. Pediatric Research 18: 911 914. 85. 1984 Lönnerdal, B., Keen, C. L. and Hurley, L. S. Zinc binding ligands and complexes in zinc metabolism. In: Advances in Nutritional Research 6 (H. H. Draper, ed.), Plenum Press, New York, pp. 139 168. 86. 1984 Keen, C. L., Lönnerdal, B. and Hurley, L. S. Manganese. In: Biochemistry of the Essential Ultratrace Elements (E. Frieden, ed.), Plenum Publishing Co., New York, pp. 89 132. 87. 1984 Keen, C. L., Baly, D. L. and Lönnerdal, B. Metabolic effects of high doses of manganese in rats. Biological Trace Element Research 6: 309 315. 88. 1985 Hurley, L. S., Reinstein, N., Lönnerdal, B. and Keen, C. L. Interaction between dietary zinc and copper during pregnancy in the rat. Nutrition Research Supplement 1: S543 S545. 89. 1985 Lönnerdal, B., Davidson, L. and Keen, C. L. Effect of varying dietary iron and zinc levels on tissue concentrations in the rat. Nutrition Research Supplement 1: S277 S280. 90. 1985 Keen, C. L., Lönnerdal, B., Zidenberg Cherr, S. and Hurley, L. S. Superoxide dismutase, lipid peroxidation and membrane stability. Nutrition Research Supplement 1: S564 S567. 91. 1985 Lönnerdal, B., Keen, C. L., Kwock, R., Hurley, L. S., Hegenauer, J. and Saltman, P. Iron bioavailability from human and cow's milk supplemented with various forms of iron. Nutrition Research Supplement 1: S224 S227. 92. 1985 Rogers, J. M., Keen, C. L. and Hurley, L. S. Zinc deficiency in pregnant Long Evans Hooded rats: Teratogenicity and tissue trace elements. Teratology 31: 89 100. 93. 1985 Baly, D. L., Keen, C. L. and Hurley, L. S. Pyruvate carboxylase and phosphoenolpyruvate carboxykinase activity in developing rats: effect of manganese deficiency. The Journal of Nutrition 115: 872 879. 94. 1985 Baly, D. L., Curry, D. L., Keen, C. L. and Hurley, L. S. Dynamics of insulin and glucagon release in rats: influence of dietary manganese. Endocrinology 116: 1734 1740. 95. 1985 Cohen, N. L., Keen, C. L., Lönnerdal, B.
and Hurley, L. S. Effects of varying dietary iron on the expression of
copper deficiency in the growing rat: Anemia, ferroxidase I and II, tissue
trace elements, ascorbic acid, and xanthine dehydrogenase. The Journal
of Nutrition 115: 633 649. 97. 1985 Lönnerdal, B. and Keen, C. L. Zinc and copper in Indian infant formulas. Reply to Gupta and Gupta. (Letter) American Journal of Diseases of Children 139: 221 222. 98. 1985 Keen, C. L., Tamura, T., Lönnerdal, B., Hurley, L. S. and Halsted, C. H. Changes in hepatic superoxide dismutase activity in alcoholic monkeys. American Journal of Clinical Nutrition 41: 929 932. 99. 1985 Amemiya, K., Hurley, L. S. and Keen, C. L. Effect of the anticarcinogenic drug 6 Mercaptopurine on mineral metabolism in the mouse. Toxicology Letters 25: 55 62. 100. 1985 Baly, D. L., Lönnerdal, B. and Keen, C. L. Effects of high doses of manganese on carbohydrate homeostasis. Toxicology Letters 25: 95 102. 101. 1985 Cohen, N. L., Keen, C. L., Hurley, L. S. and Lönnerdal, B. Determinants of copper deficiency anemia in rats. The Journal of Nutrition 115: 710 725. 102. 1985 Zidenberg Cherr, S., Hurley, L. S., Lönnerdal, B. and Keen, C. L. Manganese deficiency: Effects on susceptibility to ethanol toxicity. The Journal of Nutrition 115: 460 467. 103. 1985 Zidenberg Cherr, S., Keen, C. L. and Hurley, L. S. The effects of manganese deficiency during prenatal and postnatal development on mitochondrial structure and function in the rat. Biological Trace Element Research 7: 31 48. 104. 1985 Lefevre, M., Keen, C. L., Lönnerdal, B., Hurley, L. S., and Schneeman, B. 0. Different effects of zinc and copper deficiency on composition of plasma high density lipoprotein in rats. The Journal of Nutrition 115: 359 368. 105. 1985 Zidenberg Cherr, S., Keen, C. L., Casey, S. M. and Hurley, L. S. Developmental changes affected by Mn deficiency: Mn superoxidedismutase, Cu, Zn superoxide dismutase, Mn, Cu, Fe, and Zn in mouse tissues. Biological Trace Element Research 7: 209 222. 106. 1985 Yip, R., Reeves, J. D., Lönnerdal, B., Keen, C. L. and Dallman, P. R. Does iron supplementation compromise zinc nutrition in healthy infants? American Journal of Clinical Nutrition 42: 683 687. 107. 1985 Dubick, M. A., Keen, C. L. and Rucker, R. B. Elastin metabolism during perinatal lung development in the copper deficient rat. Experimental Lung Research 8: 227 241. 108. 1985 Uriu Hare, J. Y., Stern, J. S., Reaven, G. M. and Keen, C. L. The effects of maternal diabetes on trace element status and fetal development in the rat. Diabetes 34: 1031 1040. 109. 1985 Lönnerdal, B., Keen, C. L., Bell, J. G. and Hurley, L. S. Zinc uptake and retention from chelates and milk fractions. In: Trace Elements in Man and Animals TEMA 5 (C. F. Mills, I. Brenner and J. K. Chesters, eds.), Commonwealth Agricultural Bureaux, Farnham Royal, United Kingdom, pp. 427 430. 110. 1985 Lönnerdal, B., Bell, J. G. and Keen, C. L. Copper absorption from human milk and infant formulas: effects of copper and zinc concentrations. In: Trace Elements in Man and Animals TEMA 5 (C. F. Mills, I. Brenner and J. K. Chesters, eds.), Commonwealth Agricultural Bureaux, Farnham Royal, United Kingdom, pp. 312 315. 111. 1985 Baly, D. L., Keen, C. L., Curry, D. L. and Hurley, L. S. Effects of manganese deficiency on carbohydrate metabolism. In: Trace Elements in Man and Animals TEMA 5 (C. F. Mills, I. Brenner and J. K. Chesters, eds.), Commonwealth Agricultural Bureaux, Farnham Royal, United Kingdom, pp. 254 258. 112. 1985 Keen, C. L., Baly, D. L., Tamai, K. T. and Lönnerdal, B. Influence of manganese on glucose metabolism. In: Trace Elements in Man and Animals TEMA 5 (C. F. Mills, I. Brenner and J. K. Chesters, eds.), Commonwealth Agricultural Bureaux, Farnham Royal, United Kingdom, pp. 256 261. 113. 1985 Fransson, G. B., Hoffman, B., Lönnerdal, B. and Keen, C. L. Effects of iron and manganese supplementation of infant formula on tissue trace elements. In: Trace Elements in Man and Animals TEMA 5 (C. F. Mills, I. Brenner and J. K. Chesters, eds.), Commonwealth Agricultural Bureaux, Farnham Royal, United Kingdom, pp. 512 515. 114. 1985 Rogers, J. M., Keen, C. L. and Hurley, L. S. Zinc, copper, and manganese deficiencies in prenatal and neonatal development, with special reference to the central nervous system. In: Metal Ions in Neurology and Psychiatry Vol. 15 (S. Gabey, J. Harris, and B. T. Ho, eds.), Alan R. Liss, New York, pp. 3 34. 115. 1985 Lönnerdal, B., Bell, J. G. and Keen, C. L. Copper absorption from human milk, cow's milk and infant formulas using a suckling rat model. American Journal of Clinical Nutrition 42: 836 844. 116. 1985 Keen, C. L., Reinstein, N. H., Goudey Lefevre, J., Lefevre, M., Lönnerdal, B., Schneeman, B. 0. and Hurley, L. S. Effect of dietary copper and zinc levels on tissue copper, zinc and iron in male rats. Biological Trace Element Research 8: 123 136. 117. 1985 Dubick, M. A. and Keen, C. L. Alterations in tissue trace element and ascorbic acid metabolism in phenytoin fed rats and mice. The Journal of Nutrition 115: 1481 1487. 118. 1986 Hackman, R. M. and Keen, C. L. Changes in serum zinc and copper levels after zinc supplementation in running and nonrunning men. In: Sport, Health, and Nutrition (F. I. Katch, ed.), Human Kinetics Publishers, Inc., Champaign, IL, pp. 89 99. 119. 1986 Keen, C. L. and Hackman, R. M. Trace elements in athletic performance. In: Sport, Health, and Nutrition (F. I. Katch, ed.), Human Kinetics Publishers, Inc., Champaign, IL, pp. 51 65. 120. 1986 Clegg, M. S., Casey, S. M. and Keen, C. L. Waterborne copper toxicity in sheep. Agri Practice 7: 19 22. 121. 1986 Keen, C. L., Bell, J. G. and Lönnerdal, B. The effect of age on manganese uptake and retention from milk and infant formulas in rats. The Journal of Nutrition 116: 395 402. 122. 1986 Clegg, M. S., Lönnerdal, B., Hurley, L. S. and Keen, C. L. Analysis of whole blood manganese by flameless atomic absorption spectrophotometry and its use as an indicator of manganese status in animals. Analytical Biochemistry 157: 12 18. 123. 1986 Keen, C. L. and Lönnerdal, B. Manganese toxicity in man and experimental animals. In: Manganese in Metabolism and Enzyme Function (V. L. Schramm and F. C. Wedler, eds.), Academic Press, New York, pp 35 50. 124. 1986 Peters, A. J., Dressendorfer, R. H., Rimar, J. and Keen, C. L. Diets of endurance runners competing in a 20 day road race. The Physician and Sportsmedicine 114: 63 70. 125. 1986 Golub, M. S., Keen, C. L., Gershwin, M. E. and Vijayan, V. K. Growth, development and brain zinc levels in mice marginally or severely deprived of zinc during postembryonic brain development. Nutrition and Behavior 3: 169 180. 126. 1986 Kawamoto, J. C., Castonguay, T. W., Keen, C.
L., Stern, J. S. and Hurley, L. S. Age, sex and reproductive status alter
the severity of anorexia in zinc deficient rats. Physiology and Behavior
38: 485 493. 128. 1986 Munoz, L., Keen, C. L., Lönnerdal, B. and Dewey, K. G. Coffee intake during pregnancy and lactation in rats: maternal and pup hematological parameters and liver iron, zinc and copper concentration. The Journal of Nutrition 116: 1326 1333. 129. 1986 Peters, A. J., Keen, C. L., Lönnerdal, B. and Hurley, L. S. Zinc vitamin A interaction in pregnant and fetal rats: supplemental vitamin A does not prevent zinc deficiency induced teratogenesis. The Journal of Nutrition 116: 1765 1771. 130. 1986 Schneeman, B. 0., Lacy, D., Ney, D., Lefevre, M. L., Keen, C. L., Lönnerdal, B. and Hurley, L. S. Similar effects of zinc deficiency and restricted feeding on plasma lipids and lipoproteins. The Journal of Nutrition 116: 1859 1895. 131. 1986 Lefevre, M., Keen, C. L., Lönnerdal, B., Hurley, L. S. and Schneeman, B. 0. Copper deficiency induced hypercholesterolemia: effects on HDL subfractions and hepatic lipoprotein receptor activity in the rat. The Journal of Nutrition 116: 1735 1746. 132. 1986 Carl, G. F., Keen, C. L., Gallagher, B. B., Clegg, M. S., Littleton, W. H., Flannery, D. B. and Hurley, L. S. Association of low blood manganese concentrations with epilepsy. Neurology 36: 1584 1587. 133. 1986 Mieden, G. D., Keen, C. L., Hurley, L. S. and Klein, N. W. The effects on whole rat embryos cultured on serum from zinc and copper deficient rats. The Journal of Nutrition 116: 2424 2431. 134. 1986 Amemiya, K., Keen, C. L. and Hurley, L. S. 6 Mercaptopurine induced alterations in mineral metabolism and teratogenesis. Teratology 34: 321 334. 135. 1986 Masters, D. G., Keen, C. L., Lönnerdal, B. and Hurley, L. S. Release of zinc from maternal tissues during zinc deficiency or simultaneous zinc and calcium deficiency in the pregnant rat. The Journal of Nutrition 116: 2148 2154. 136. 1986 Amemiya, K., Hurley, L. S. and Keen, C. L. The effect of 6 mercaptopurine on mineral and metallothionein metabolism in the mouse. Biological Trace Element Research 11: 161 176. 137. 1986 Baly, D. L., Keen, C. L. and Hurley, L. S. Effects of manganese deficiency on pyruvate carboxylase and phosphoenolpyruvate carboxykinase activity and carbohydrate homeostasis in adult rats. Biological Trace Element Research 11:201 212. 138. 1987 Vruwink, K. G., Keen, C. L., Gershwin, M. E. and Hurley, L. S. Studies of nutrition and autoimmunity. V. Failure of zinc deprivation to alter autoantibody production when initiated in disease established mice. The Journal of Nutrition 117: 177 182. 139. 1987 Dubick, M. A., Hunter, G. C., Casey, S. M. and Keen, C. L. Aortic ascorbic acid, trace elements, and superoxide dismutase activity in human aneurysmal and occlusive disease. The Proceedings of the Society for Experimental Biology and Medicine 184: 138 143. 140. 1987 Kawano, J., Ney, D. N., Keen, C. L. and Schneeman, B. 0. Altered high density lipoprotein composition in manganese deficient Sprague Dawley and Wistar rats. The Journal of Nutrition 117: 902 906. 141. 1987 Reinstein, N. H., Lönnerdal, B., Keen, C. L., Schneeman, B. 0. and Hurley, L. S. The effect of varying dietary zinc levels on the concentration and localization of zinc in rat bile pancreatic fluid. The Journal of Nutrition 117: 1060 1066.
143. 1987 Keen, C. L. and Feldman, B. F. Measurement of zinc and copper in plasma: Potential negative effects of anticoagulant choice on analyzed values. Agri Practice 8: 4 5. 144. 1987 Golub, M. S., Gershwin, M. E., Donald, J. M., Negri, S. and Keen, C. L. Maternal and developmental toxicity of chronic aluminum exposure in mice. Fundamental and Applied Toxicology 8: 346 357. 145. 1987 Keen, C. L. and Hurley, L. S. Effects of zinc deficiency on prenatal and postnatal development. Neurotoxicology 8: 379 388. 146. 1987 Keen, C. L., Lowney, P., Gershwin, M. E., Hurley, L. S. and Stern, J. S. Dietary magnesium intake influences exercise capacity and hematological parameters in rats. Metabolism 36: 788 793. 147. 1987 Keen, C. L. and Leach, R. M. Manganese. In: Handbook on Toxicity of Inorganic Compounds (H. G. Seiler and H. Sigel, eds.), Marcel Dekker, Inc., New York, pp. 405 415. 148. 1987 Keen, C. L., Clegg, M. S., Ferrell, F., Hunter, G. C. and Dubick, M. A. Hypertension induced alterations in copper and zinc metabolism: A link to vascular disease? In: Biology of Copper Complexes (J. R. J. Sorenson, ed.), Humana Press, Clifton, NJ, pp. 141 153. 149. 1987 Zidenberg Cherr, S., Parks, N. J. and Keen, C. L. Tissue and subcellular distribution of bismuth radiotracer in the rat: Considerations of cytotoxicity and microdosimetry for bismuth radiopharmaceuticals. Radiation Research 111: 119 129. 150. 1987 Feldman, B. F. and Keen, C. L. Contamination during zinc and copper analysis. American Journal of Veterinary Research (Letter) 48: 154. 151. 1987 Clegg, M. S., Ferrell, F. and Keen, C. L. Hypertension induced alterations in copper and zinc metabolism in Dahl rats. Hypertension 9: 624 628. 152. 1987 Lönnerdal, B., Keen, C. L., Bell, J. G. and Sandstrom, B. Manganese uptake and retention: experimental animal and human studies. In: Nutritional Bioavailability of Manganese (C. Kies, ed.), American Chemical Society, Washington, DC, pp. 9 20. 153. 1987 Carl, G. F., Keen, C. L., Gallagher, B. B. and Hurley, L. S. Manganese metabolism in epilepsy: normal or abnormal? In: Nutritional Bioavailability of Manganese (C. Kies, ed.), American Chemical Society, Washington, DC, pp. 105 111. 154. 1987 Zidenberg Cherr, S. and Keen, C. L. Enhanced tissue lipid peroxidation: a mechanism underlying pathologies associated with dietary manganese deficiency. In: Nutritional Bioavailability of Manganese (C. Kies, ed.), American Chemical Society, Washington, DC, pp. 56 66. 155. 1987 Keen, C. L., Zidenberg Cherr, S. and Lönnerdal, B. Dietary manganese toxicity and deficiency: effects on cellular manganese metabolism. In: Nutritional Bioavailability of Manganese (C. Kies, ed.), American Chemical Society, Washington, DC, pp. 21 34. 156. 1987 Gershwin, M. E., Keen, C. L., Fletcher, M. P. and Hurley, L. S. Nutrition and immunity. Proceedings of the Nutrition Society of Australia 12: 1 12. 157. 1988 Elfant, M. and Keen, C. L. Vanadium toxicity
in adult and developing rats: Role of peroxidative damage. Biological
Trace Element Research 14: 193 208. 159. 1987 Hurley, L. S. and Keen, C. L. Manganese. In: Trace Elements in Human Health and Animal Nutrition Volume 1 (E. Underwood and W. Mertz, eds.), Academic Press, New York, pp. 185 223. 160. 1987 Bell, J. G., Keen, C. L. and Lönnerdal, B. Effect of infant cereals on zinc and copper absorption during weaning. American Journal of Diseases of Children 141: 1128 1132. 161. 1987 Katz, R. L., Keen, C. L., Litt, I. F., Hurley, L. S., Kellams Harrison, K. M. and Glader, L. J. Zinc deficiency in anorexia nervosa. Journal of Adolescent Health Care 8: 400 406. 162. 1988 McDonald, R. and Keen, C. L. Iron, zinc and manganese nutrition and athletic performance. Sports Medicine 5: 171 184. 163. 1988 Morgan, P. N., Keen, C. L., Calvert, C. C. and Lonnerdal, B. The effect of varying dietary zinc intake of weanling mouse pups during recovery from early undernutrition on growth, body composition and composition of gain. The Journal of Nutrition 118: 690 698. 164. 1988 Morgan, P. N., Keen, C. L. and Lonnerdal, B. The effect of varying dietary zinc intake of weanling mouse pups during recovery from early undernutrition on tissue mineral concentrations, relative organ weights, hematological variables, and muscle composition. The Journal of Nutrition 118: 699 711. 165. 1988 Lowney, P., Gershwin, M. E., Hurley, L. S., Stern, J. S. and Keen, C. L. The effect of variable magnesium intake on potential factors influencing endurance capacity. Biological Trace Element Research 16: 1 18. 166. 1988 Munoz, L., Lönnerdal, B., Keen, C. L. and Dewey, K. G. Coffee consumption as a factor in iron deficiency anemia among pregnant women and their offspring in Costa Rica. American Journal of Clinical Nutrition 48: 645 651. 167. 1988 Reis, B. I., Keen, C. L., Lönnerdal, B. and Hurley, L. S. Mineral composition and zinc metabolism in female mice of varying age and reproductive status. The Journal of Nutrition 118: 349 361. 168. 1988 Lönnerdal, B., Bell, J. G., Hendrickx, A. G., Burns, R. A. and Keen, C. L. Effect of phytate removal on zinc absorption from soy formula. American Journal of Clinical Nutrition 48: 1301 1306. 169. 1988 Hurley, L. S. and Keen, C. L. Fetal and neonatal development in relation to maternal trace element nutrition: manganese, zinc and copper. Vitamins and minerals in pregnancy and lactation. In: Nestle Nutrition Workshop Series No. 16 (H. Berger, ed.), pp. 215 230 170. 1988 Keen, C. L., Golub, M. S., Gershwin, M. E., Lönnerdal, B. and Hurley, L. S. Long term marginal zinc deprivation in rhesus monkeys: III. Use of liver biopsy in the assessment of zinc status. American Journal of Clinical Nutrition 47: 1041 1045. 171. 1988 Zidenberg Cherr, S., Benak, P. A., Hurley, L. S. and Keen, C. L. Altered mineral metabolism: a mechanism underlying the fetal alcohol syndrome in rats. Drug Nutrient Interactions 5: 257 274. 172. 1988 Fletcher, M. P., Gershwin, M. E., Keen, C. L. and Hurley, L. S. Trace element deficiencies and immune responsiveness in human and animal models. In: Contemporary Issues in Clinical Nutrition. Vol. II. Nutrition and Immunology (Chandra, R. J., ed.), Alan R. Liss, New York, pp. 215 239.
174. 1988 Vruwink, K. G., Hurley, L. S., Gershwin, M. E. and Keen, C. L. Gestational zinc deficiency amplifies the regulation of metallothionein induction in adult mice. Proceedings of the Society for Experimental Biology and Medicine 188: 30 34. 175. 1988 Peters, J. M., Lönnerdal, B. and Keen, C. L. Effect of the antihypertensive drug hydralazine on mineral metabolism in the rat. Toxicology Letters 41: 193 202. 176. 1988 Oster, M. H., Castonguay, T. W., Keen, C. L. and Stern, J. S. Circadian rhythm of corticosterone in diabetic rats. Life Sciences 43: 1643 1645. 177. 1988 Chung, K., Romero, N., Tinker, D., Keen, C. L., Amemiya, K. and Rucker, R. B. Role of copper in the regulation and accumulation of superoxide dismutase and metallothionein in rat liver. The Journal of Nutrition 118: 859 864. 178. 1988 Graham, T. W., Holmberg, C. A., Keen, C. L., Thurmond, M. C. and Clegg, M. S. A pathologic and toxicologic evaluation of veal calf mortality associated with high levels of zinc feeding. Veterinary Pathology 25: 484 491. 179. 1988 Dubick, M. A., Zidenberg Cherr, S., Rucker, R. B. and Keen, C. L. Superoxide dismutase activity in lung from copper and manganese deficient mice exposed to ozone. Toxicology Letters 42: 149 157. 180. 1988 Zidenberg Cherr, S., Rosenbaum, J. and Keen, C. L. Influence of ethanol consumption on maternal fetal transfer of zinc in pregnant rats on day 14 of pregnancy. The Journal of Nutrition 118: 865 870. 181. 1988 Oteiza, P. I., Hurley, L. S., Lönnerdal, B. and Keen, C. L. Marginal zinc deficiency affects maternal brain microtubule assembly in rats. The Journal of Nutrition 118: 735 738. 182. 1988 Clegg, M. S., Keen, C. L. and Hurley, L. S. Biochemical pathologies of zinc deficiency. In: Zinc in Human Biology (C. F. Mills, ed.), Springer Verlag, New York, pp. 129 145. 183. 1988 Keen, C. L. and Hurley, L. S. Zinc and reproduction: Effect on fetal and postnatal development. In: Zinc in Human Biology (C. F. Mills, ed.), Springer Verlag, New York, pp. 183 220. 184. 1988 Graham, T. W., Keen, C. L., Holmberg, C. A., Thurmond, M. C. and Clegg, M. S. An episode of zinc toxicosis in milk fed Holstein bull calves: pathologic and toxicologic considerations. In: Trace Elements in Man and Animals TEMA 6 (Hurley, L. S., Keen, C. L., Lönnerdal, B. and Rucker, R. B., eds.), Plenum Press, New York, pp. 697 698. 185. 1988 Uriu Hare, J. Y., Stern, J. S. and Keen, C. L. Effects of maternal dietary zinc on the expression of diabetes induced teratogenicity in the rat. In: Trace Elements in Man and Animals TEMA 6 (Hurley, L. S., Keen, C. L., Lönnerdal, B. and Rucker, R. B., eds.), Plenum Press, New York, pp. 633 634. 186. 1988 Oteiza, P. I., Keen, C. L., Lönnerdal, B. and Hurley, L. S. Marginal Zn deficiency affects pup brain microtubule assembly in rats. In: Trace Elements in Man and Animals TEMA 6 (Hurley, L. S., Keen, C. L., Lönnerdal, B. and Rucker, R. B., eds.), Plenum Press, New York, pp. 631 632. 187. 1988 Zidenberg Cherr, S., Rosenbaum, J. and Keen,
C. L. Altered mineral metabolism as a mechanism underlying the expression
of fetal alcohol syndrome in rats. In: Trace Elements in Man and Animals
TEMA 6 (Hurley, L. S., Keen, C. L., Lönnerdal, B. and Rucker, R.
B., eds.), Plenum Press, New York, pp. 613 614. 189. 1988 Morgan, P. N., Keen, C. L., Cardinet, G. H., III and Lönnerdal, B. Effects of varying dietary zinc in mice during recovery from undernutrition. In: Trace Elements in Man and Animals TEMA 6 (Hurley, L. S., Keen, C. L., Lönnerdal, B. and Rucker, R. B., eds.), Plenum Press, New York, pp. 611 612. 190. 1988 Gershwin, M. E., Keen, C. L., Fletcher, M. P. and Hurley, L. S. Trace element deficiencies and immune responses. In: Trace Elements in Man and Animals TEMA 6 (Hurley, L. S., Keen, C. L., Lönnerdal, B. and Rucker, R. B., eds.), Plenum Press, New York, pp. 85 90. 191. 1988 Brandt, M., Keen, C. L., Ash, D. E. and Schramm, V. L. Transport, subcellular distribution and export of Mn(II) in rat liver and hepatocytes. In: Trace Elements in Man and Animals TEMA 6 (Hurley, L. S., Keen, C. L., Lönnerdal, B. and Rucker, R. B., eds.), Plenum Press, New York, pp. 125 128. 192. 1988 Keen, C. L., Clegg, M. S., Lönnerdal, B. and Hurley, L. S. The role of zinc in prenatal and postnatal development. In: Trace Elements in Man and Animals TEMA 6 (Hurley, L. S., Keen, C. L., Lönnerdal, B. and Rucker, R. B., eds.), Plenum Press, New York, pp. 203 208. 193. 1988 Hurley, L. S., Keen, C. L., Lönnerdal, B. and Rucker, R. B., Editors. Trace Elements in Man and Animals VI. Plenum Press, New York, pp. 724. 194. 1989 McDonald, R. and Keen, C. L. Iron, zinc and magnesium nutrition and athletic performance. Performance Enhancement in Sport, pp. 47 60. (Reprint of publication no. 162.) 195. 1989 Amemiya, K., Hurley, L. S. and Keen, C. L. Effect of 6 mercaptopurine on 65Zn distribution in the pregnant rat. Teratology 39: 387 393. 196. 1989 Gershwin, M. E., Keen, C. L., Fletcher, M. P. and Hurley, L. S. Nutrition factors. In: Natural Immunity (Nelson, D., ed.), Academic Press, New York. pp. 440 472. 197. 1989 Bell, J. G., Keen, C. L. and Lönnerdal, B. Higher retention of manganese in suckling than in adult rats is not due to maturational differences in manganese uptake by rat small intestine. Journal of Toxicology and Environmental Health 26: 387 398. 198. 1989 Zidenberg Cherr, S., Clegg, M. S., Parks, N. J. and Keen, C. L. Localization of bismuth radiotracer in rat kidney following exposure to bismuth. Biological Trace Element Research 19: 185 194. 199. 1989 Uriu Hare, J. Y., Stern, J. S. and Keen, C. L. The effect of diabetes on the molecular localization of maternal and fetal zinc and copper metalloprotein in the rat. Biological Trace Element Research 18: 71 79. 200. 1989 Keen, C. L. and Graham, T. W. Trace elements. In: Clinical Biochemistry of Domestic Animals, 4th Ed. (Kaneko, J. J., ed.), Academic Press, San Diego, pp. 753 795. 201. 1989 Keen, C. L., Peters, J. M. and Hurley, L. S. The effect of valproic acid on 65Zn distribution in the pregnant rat. The Journal of Nutrition 119: 607 611. 202. 1989 Golub, M. S., Donald, J. M., Gershwin, M. E. and Keen, C. L. Effects of aluminum ingestion on spontaneous motor activity of mice. Neurotoxicology and Teratology 11: 231 235. 203. 1989 Oteiza, P. I., Golub, M. S., Gershwin, M. E., Donald, J. M. and Keen, C. L. The influence of high dietary aluminum on brain microtubule polymerization in mice. Toxicology Letters 47: 279 285. 204. 1989 Donald, J. M., Golub, M. S., Gershwin, M. E. and Keen, C. L. Neurobehavioral effects in offspring of mice given excess aluminum in diet during gestation and lactation. Neurotoxicology and Teratology 11: 345 351. 205. 1989 Zidenberg Cherr, S., Dreith, D. and Keen, C. L. Copper status and adriamycin treatment: effects on antioxidant status in mice. Toxicology Letters 48: 201 212. 206. 1989 Yoshida, S., Gershwin, M. E., Keen, C. L., Donald, J. M. and Golub, M. S. The influence of aluminum on resistance to Listeria Monocytogenes in Swiss-Webster mice. International Archives of Allergy and Applied Immunology 89:404 409. 207. 1989 Uriu Hare, J. Y., Keen, C. L., Applegate, E. A. and Stern, J. S. The influence of moderate exercise in diabetic and normal pregnancy on maternal and fetal outcome in the rat. Life Sciences 45: 647 654. 208. 1989 Davidsson, L., Lönnerdal, B., Sandstrom, B., Kunz, C. and Keen, C. L. Identification of transferrin as the major plasma carrier protein for manganese introduced orally or intravenously or after in vitro addition in the rat. The Journal of Nutrition 119: 1461 1464. 209. 1989 Keen, C. L. and Finley, D. Biographical Article: Lucille Shapson Hurley. The Journal of Nutrition 119: 1875 1879. 210. 1989 Uriu Hare, J. Y., Stern, J. S. and Keen, C. L. Influence of maternal dietary Zn intake on expression of diabetes induced teratogenicity in rats. Diabetes 38: 1282 1290. 211. 1989 Oteiza, P. I., Cuellar, S., Lönnerdal, B., Hurley, L. S. and Keen, C. L. Influence of maternal dietary zinc intake on in vitro tubulin polymerization in fetal brain. Teratology 41: 97 104. 212. 1989 Carl, G. F., Critchfield, J. W., Thompson, J. L., McGinnis, L. S., Wheeler, G. A., Gallagher, B. B., Holmes, G. L., Hurley, L. S. and Keen, C. L. Effect of kainate induced seizures on tissue trace element concentrations in the rat. Neuroscience 33: 223 227. 213. 1989 Keen, C. L., Lönnerdal, B., Golub, M. S., Uriu Hare, J. Y., Olin, K. L., Hendrickx, A. G. and Gershwin, M. E. Influence of marginal maternal zinc deficiency on pregnancy outcome and infant zinc status in rhesus monkeys. Pediatric Research 26: 470 477. 214. 1989 Mameesh, M. S., Keen, C. L. and Hurley, L. S. Effect of zinc or copper deficiency on erythrocyte purine nucleoside phosphorylase and pyruvate kinase activity in the rat. International Journal for Vitamin and Nutrition Research 59: 390 395. 215. 1989 Harris, W. R. and Keen, C. L. Calculations of the distribution of zinc in a computer model of human serum. The Journal of Nutrition 119:1677 1682. 216. 1990 Oteiza, P. I., Hurley, L. S., Lönnerdal, B. and Keen, C. L. Effects of marginal zinc deficiency on microtubule polymerization in the developing rat brain. Biological Trace Element Research 24: 13 23. 217. 1990 Keen, C. L. and Gershwin, M. E. Nutrient modulation of autoimmune disease. Annals of the New York Academy of Sciences 587: 208 217. 218. 1990 Lönnerdal, B., Keen, C. L., Hendrickx, A. G., Golub, M. S. and Gershwin, M. E. Influence of dietary zinc and iron on zinc retention in pregnant rhesus monkeys and their infants. Obstetrics and Gynecology 75: 369 374.
220. 1990 Lowney, P., Stern, J. S., Gershwin, M. E. and Keen, C. L. Magnesium deficiency and blood 2,3 diphosphoglycerate concentrations in sedentary and exercised male Osborne Mendel rats. Metabolism 39: 837 841. 221. 1990 Zidenberg Cherr, S., Halsted, C. H., Olin, K. L., Reisenauer, A. M. and Keen, C. L. The effect of chronic alcohol ingestion on free radical defense in the miniature pig. The Journal of Nutrition 120: 213 217. 222. 1990 Fraga, C. G., Oteiza, P. I., Golub, M. S., Gershwin, M. E. and Keen, C. L. Effects of aluminium on brain lipid peroxidation. Toxicology Letters 51: 213 219. 223. 1990 Keen, C. L. and Zidenberg Cherr, S. Manganese. In: Present Knowledge in Nutrition (Brown, M. L., ed.) International Life Science Institute, Nutrition Foundation, Washington, D.C., pp. 279 286. 224. 1990 Keen, C. L. and Gershwin, M. E. Zinc deficiency and immune function. Annual Review of Nutrition 10: 415 431. 225. 1990 Walter, R. M., Oster, M. H., Lee, T. J., Flynn, N. and Keen, C. L. Zinc status in human immunodeficiency virus infection. Life Sciences 46: 1597 1600. 226. 1990 Dubick, M. A., Keen, C. L., Conteas, C. N. and McMahon, M. J. Trace element and mineral metabolism in acute pancreatitis. The Journal of Trace Elements in Experimental Medicine 3: 125 134. 227. 1990 Carl, G. F., Critchfield, J. W., Thompson, J. L., Holmes, G. L., Gallagher, B. B. and Keen, C. L. Genetically epilepsy prone rats are characterized by altered tissue trace element concentrations. Epilepsia 31: 247 252. 228. 1990 Walter, R. M. and Keen, C. L. SI units: A wholehearted effort is needed. (Letter) Journal of American Medical Association 264: 974. 229. 1990 Domingo, J. L., Llobet, J. M., Gomez, M., Corbella, J. and Keen, C. L. Effects of oral vanadium administration in streptozotocin diabetic rats. In: Metal Ions in Biology and Medicine. Proceedings of the First International Symposium on Metal Ions in Biology and Medicine (Collery, P., Poirier, L. A., Manfait, M. and Etienne, J. C., eds), John Libbey Eurotext, Reims, France, pp. 312 314. 230. 1990 Rogers, J. M., Oteiza, P. and Keen, C. L. Zinc and manganese deficiencies in prenatal and neonatal development, with special reference to the central nervous system. In: (Mal)Nutrition and the Infant Brain (Gelder, N. M., Butterworth, R. F. and Drujan, B. D., eds), Wiley Liss, Inc., pp. 225 236. 231. 1990 Lönnerdal, B., Keen, C. L., Bell, J. G., Golub, M. S., Hendrickx, A. G. and Gershwin, M. E. Effect of marginal maternal zinc intake on zinc absorption and growth of 3 month old infant rhesus monkeys. American Journal of Diseases of Children 144: 1007 1010. 232. 1990 Golub, M. S., Gershwin, M. E., Lönnerdal, B., Keen, C. L., Hurley, L. S. and Hendrickx, A. G. Problems associated with long term feeding of purified diets in Rhesus monkeys. Primates 31: 579 588. 233. 1991 Zidenberg Cherr, S., and Keen, C. L. Essential trace elements as antioxidant processes. In: Trace Elements, Micronutrients and Free Radicals (Dreosti, I. E., ed.) The Humana Press Inc., New Jersey, pp. 107 127. 234. 1991 Dressendorfer, R. H., Keen, C. L., Wade, C. E., Claybaugh, J. R. and Timmis, G. C. Development of runner's anemia during a 20 day road race: Effects of iron supplements. International Journal of Sports Medicine 12: 332 336. 235. 1991 Golub, M. S., Keen, C. L., Hendrickx, A. G. and Gershwin, M. E. Food preference of young Rhesus monkeys fed marginally zinc deficient diets. Primates 32: 49 59. 236. 1991 Vruwink, K. G., Fletcher, M. P., Keen, C. L., Golub, M. S., Hendrickx, A. G. and Gershwin, M. E. Moderate zinc deficiency in Rhesus monkeys: An intrinsic defect of neuothophil chemotaxis corrected by zinc repletion. Journal of Immunology 146: 244 249. 237. 1991 Halsted, C. H. and Keen, C. L. Alcoholism and micronutrient metabolism and deficiencies. European Journal of Gastroenterology and Hepatology 2: 399 405. 238. 1991 Reis, B. L., Keen, C. L., Lönnerdal, B. and Hurley, L. S. Longitudinal changes in the mineral composition of mouse milk and the relationship to zinc metabolism of the suckling neonate. The Journal of Nutrition 121: 687 699. 239. 1991 Reis, B. L., Keen, C. L., Lönnerdal, B. and Hurley, L. S. Mineral status of mice suckling early , mid and late lactating foster dams. The Journal of Nutrition 121: 700 710. 240. 1991 Hunter, G. C., Dubick, M. A., Keen, C. L. and Eskelson, C. D. Effects of hypertension on aortic antioxidant status in human abdominal aneurysmal and occlusive disease. Proceedings of the Society for Experimental Biology and Medicine 196: 273 279. 241. 1991 Domingo, J. L., Gomez, M., Llobet, J. M., Corbella, J. and Keen, C. L. Improvement of glucose homeostasis by oral vanadyl or vanadate treatment in diabetic rats is accompanied by negative side effects. Pharmacology and Toxicology 68: 249 253. 242. 1991 Graham, T. W., Feldman, B. F., Farver, T. B., Labavitch, F., O'Neill, S. L., Thurmond, M. C., Keen, C. L. and Holmberg, C. A. Zinc toxicosis of Holstein veal calves and its relationship to haematological change and an associated thrombotic state. Comparitive Haematology International 1: 121 128. 243. 1991 Romero Chapman, N., Lee, J., Tinker, D., Uriu Hare, J. Y., Keen, C. L. and Rucker, R. B. Purification, properties and influence of dietary copper on accumulation and functional activity of lysyl oxidase in rat skin. Biochemical Journal 75: 657 662. 244. 1991 Zidenberg Cherr, S., Olin, K. L., Villanveva, J., Tang, A., Phinney, S. D., Halsted, C. H. and Keen, C. L. Ethanol induced changes in hepatic free radical defense mechanisms and fatty acid composition in the miniature pig. Hepatology 13: 1185 1192.
246. 1991 Keen, C. L., German, B. J., Mareschi, J P. and Gershwin, M. E. Nutritional modulation of murine models of autoimmunity. Rheumatic Disease Clinics of North America 17: 223 234. 247. 1991 Zidenberg Cherr, S., Han, B., Dubick, M. A. and Keen, C. L. Influence of dietary induced copper and manganese deficiency on ozone induced changes in lung and liver antioxidant systems. Toxicology Letters 57: 81 90. 248. 1991 Gershwin, M. E., Keen, C. L., Mareschi, J P. and Fletcher, M. P. Trace metal nutrition and the immune response. Comprehensive Therapy 17: 27 34. 249. 1991 Dubick, M. A. and Keen, C. L. Influence of nicotine on tissue trace element concentrations and tissue antioxidant defense. Biological Trace Element Research 31: 97 109. 250. 1991 Domingo, J. L., Gomez, M., Llobet, J. M., Corbella, J. and Keen, C. L. Oral vanadium administration to streptozotocin diabetic rats has marked negative side effects which are independent of the form of vanadium used. Toxicology 66: 279 287. 251. 1991 Rosenbaum, J. S., Zidenberg Cherr, S. and Keen, C. L. Influence of copper status on the response to acute ethanol exposure in rats. Alcohol 8: 473 479. 252. 1991 Dubick, M. A., Hunter, G. C. and Keen, C. L. Trace element and mineral concentrations in serum and aorta from patients with abdominal aneurysmal or occlusive disease. Journal of Trace Elements in Experimental Medicine 4: 173 182. 253. 1991 Walter, R. M., Uriu Hare, J. Y., Olin, K. L., Oster, M. H., Anawalt, B. D., Critchfield, J. W. and Keen, C. L. Copper, zinc, manganese and magnesium status and complications of diabetes mellitus. Diabetes Care 14: 1050 1056. 254. 1991 Garrow, T. A., Clegg, M. S., Metzler, G. and Keen, C. L. Influence of hypertension and dietary copper on indexes of copper status in rats. Hypertension 17: 793 797. 255. 1991 Domingo, J. L., Ortega, A., Llobet, J. M. and Keen, C. L. No improvement of glucose homeostasis in diabetic rats by vanadate treatment when given by gauage. Trace Elements in Medicine 8: 181 186. 256. 1991 Oteiza, P. I. and Keen, C. L. Glycerophospholipid synthesis in zinc deficient rats. In: Trace Elements in Man and Animals TEMA 7 (B. Momcilovic, ed.), Institute for Medical Research and Occupational Health, University of Zagreb, Croatia, Yugoslavia, pp. 18 28. 257. 1991 Peters, J. M., Wiley, L. M., Zidenberg Cherr, S. and Keen, C. L. Influence of short term maternal zinc deficiency on the in vitro development of preimplantation mouse embryos. Proceedings of the Society for Experimental Biology and Medicine 198: 561 568. 258. 1991 Daston, G. P., Overman, G. J., Taubeneck, M. W., Lehman McKeeman, L. D., Rogers, J. M. and Keen, C. L. The role of metallothionein induction and altered zinc status in maternally mediated developmental toxicity: Comparison of the effects of urethane and styrene in rats. Toxicology and Applied Pharmacology 110: 450 463. 259. 1991 Halpern, G. M., VandeWater, J., Delabroise, A M., Keen, C. L. and Gershwin, M. E. Comparative uptake of calcium from milk and a calcium rich mineral water in lactose intolerant adults: Implications for treatment of osteoporosis. American Journal of Preventive Medicine 7: 379 383. 260. 1991 Halpern, G. M., Vruwink, K. G., Van de Water, J., Keen, C. L. and Gershwin, M. E. Influence of long term yoghurt consumption in young adults. International Journal of Immunotherapy 7: 205 210. 261. 1992 Golub, M. S., Tarantal, A. F., Gershwin, M. E., Keen, C. L., Hendrickx, A. G. and Lonnerdal, B. Ultrasound evaluation of fetuses of zinc deprived monkeys (Macaca mulatta). American Journal of Clinical Nutrition 55: 734 740. 262. 1992 Golub, M. S., Keen, C. L. and Gershwin, M. E. Neurodevelopmental effect of aluminium in mice: Fostering studies. Neurobehavioral Toxicology and Teratology 14: 177 182. 263. 1992 Domingo, J. L., Gomez, M., Sanchez, D. J., Llobet, J. M. and Keen, C. L. Tiron administration minimizes the toxicity of vanadate but not its insulin mimetic properties in diabetic rats. Life Sciences 50: 1311 1317. 264. 1992 Golub, M. S., Han B., Keen, C. L., and Gershwin, M. E. Effects of dietary aluminum excess and manganese deficiency on neurobehavioral endpoints in adult mice. Toxicology and Applied Pharmacology 112: 154 160. 265. 1992 Keen, C.L., Uriu Hare, J.Y., Swan, S.H., and Neutra, R.R. The effects of water source on reproductive outcome in Fisher 344 rats. Epidemiology 3: 130 133. 266. 1992 Taubeneck, M. W., Domingo, J. L., Llobet, J. M., and Keen, C. L. Meso 2,3 dimencaptosuccinic acid (DMSA) affects maternal and fetal copper metabolism in Swiss mice. Toxicology 72: 27 40. 267. 1992 Keen, C. L. Maternal factors affecting teratogenic response: A need for assessment. Teratology 46: 15 21. 268. 1992 Arce, D. S. and Keen, C. L. Reversible and persistent consequences of copper deficiency in developing mice. Reproductive Toxicology 6: 211 221. 269. 1992 Liu, H., Oteiza, P. I., Gershwin, M. E., Golub, M. S., and Keen, C. L. Effects of maternal marginal zinc deficiency on myelin protein profiles in the suckling rat and infant rhesus monkey. Biological Trace Element Research 34: 55 66. 270. 1992 Graham, T. W. and Keen, C. L. More on zinc and copper in dairy rations. Journal of American Veterinary Medical Association (Letter) 200: 760 762. 271. 1992 Critchfield, J. W. and Keen, C. L. Manganese+2 exhibits dynamic binding to multiple ligands in human plasma. Metabolism 41: 1087 1092. 272. 1992 Uriu Hare, J. Y., Walter, R. M., and Keen, C. L. 65Zinc metabolism is altered during diabetic pregnancy in rats. The Journal of Nutrition 122: 1988 1998. 273. 1992 Llobet, J. M., Gómez, M., Sánchez, D. J., Domingo, J. L., Corbella, J., and Keen, C. L. Efficacy of Tiron on the mobilization of vanadium in diabetic rats after oral aministration of metavanadate. In: Metal Ions in Biology and Medicine (J. Anastassopoulou, Ph. Collery, J. C. Etienne, Th. Theophanides, eds.), Vol. 2, John Libbey Eurotext, Paris, pp. 329-330.. 274. 1993 Vruwink, K. G., Keen, C. L., Gershwin, M. E., Mareschi, J. P., and Hurley, L. S. The effect of experimental zinc deficiency on development of the immune system. In: Nutritional Modulation of the Immune Response (S. Cunningham Rundles, ed.), Marcel Dekker, New York, pp. 263 279. 275. 1993 DiPaolo, D., Graham, T. W., Mohr, F. C., Stabenfeldt, G. H., and Keen, C. L. Influence of zinc on 17 estradiol and progesterone release from dispersed rat ovarian cells. Journal of Trace Elements in Experimental Medicine 6:147-154. 276. 1993 Keen, C. L. and Zidenberg-Cherr, S. Manganese. In: Encyclopaedia of Food Science, Food Technology and Nutrition. Academic Press, London, pp. 2863-2868. 277. 1993 Critchfield, J. W., Carl, G. F., and Keen, C. L. Anticonvulsant-induced changesin tissue manganese, zinc, copper and iron concentrations in Wistar rats. Metabolism 42: 907-910. 278. 1993 Keen, C. L. The effects of exercise and heat on mineral metabolism and requirements. In: Nutrition Needs in Hot Environments (B. M. Marriott, ed.), National Academy Press, Washington, DC, pp. 117-135. 279. 1993 Carl, G. F., Blackwell, L. K., Barnett, F. C., Thompson, L. A., Rissinger, C. J., Olin, K. L., Critchfield, J. W., Keen, C. L., and Gallagher, B. B. Manganese and epilepsy: brain glutamine synthetase and liver arginase activities in genetically epilepsy prone and chronically seizured rats. Epilepsia 34:441-446. 280. 1993 Vruwink, K. G., Gershwin, M. E., and Keen, C. L. Effects of gestational zinc deficiency in mice on growth and immune function. Journal of Nutritional Immunology 2: 25-41. 281. 1993 Critchfield, J. W., Carl, G. F., and Keen, C. L. The influence of manganese supplementation on seizure onset and severity, and brain monoamines in the genetically epilepsy prone rat. Epilepsy Research 14: 3-10. 282. 1993 Arce, D. S. and Keen, C. L. Effects of marginal and severe iron deficiency on hepatic proteins in developing rats are reversible with dietary iron repletion. Reproductive Toxicology 7: 61-72. 283. 1993 Keen, C. L., Taubeneck, M. W., Daston, G. P., Rogers, J. M., and Gershwin, M. E. Primary and secondary zinc deficiency as factors underlying abnormal CNS development. Annals of the New York Academy of Sciences 678: 37-47. 284. 1993 Oteiza, P. I., Keen, C. L., Han, B., and Golub, M. S. Aluminum accumulation and neurotoxicity in Swiss-Webster mice after chronic dietary exposure to aluminum and citrate. Metabolism 42: 1296-1300. 285. 1993 Oteiza, P. I., Fraga, C. G., and Keen, C. L. Aluminum has both oxidant and antioxidant effects in mouse brain membranes. Archives of Biochemistry and Biophysics 300: 517-521. 286. 1993 Keen, C. L., Lönnerdal, B., Golub, M. S., Olin, K. L., Graham, T. W., Uriu-Hare, J. Y., Hendrickx, A. G., and Gershwin, M. E. Effect of the severity of maternal zinc deficiency on pregnancy outcome and infant zinc status in rhesus monkeys. Pediatric Research 33: 233-241. 287. 1993 Golub, M. S., Han, B., Keen, C. L., and Gershwin, M. E. Developmental patterns of aluminum in mouse brain and effects of dietary aluminum excess on manganese deficiency. Toxicology 81: 33-47. 288. 1993 Trapp, C. L., Chang, C. C., Halpern, G. M., Keen, C. L., and Gershwin, M. E. The influence of chronic yogurt consumption on populations of young and elderly adults. International Journal of Immunotherapy 9: 53-64. 289. 1993 Gacheru, S., McGee, C., Uriu-Hare, J. Y., Kosonen, T., Packman, S., Tinker, D., Krawetz, S. A., Reiser, K., Keen, C. L., and Rucker, R. B. Expression and accumulation of lysyl oxidase, elastin, and type I procollagen in human Menkes and Mottled mouse fiboblasts. Archives of Biochemistry and Biophysics 301: 325-329. 290. 1993 Couzy, F., Keen, C., Gershwin, M. E., and Mareschi, J. P. Nutritional implications of the interactions between minerals. Progress in Food and Nutrition Science 17: 65-87.
292. 1993 Berger, A., German, J. B., Chiang, B-Z., Ansari, A. A., Keen, C. L., Fletcher, M. P., and Gershwin, M. E. Influence of feeding unsaturated fats on growth and immune status of mice. The Journal of Nutrition 123:225-233. 293. 1993 Olin, K. L., Shigenaga, M. K., Ames, B. N., Golub, M. S., Gershwin, M. E., Hendrickx, A. G., and Keen, C. L. Maternal dietary zinc influences DNA strand break and 8-hydroxy-2'-deoxyguanosine levels in infant rhesus monkey liver. Proceedings of the Society for Experimental Biology and Medicine 203:461-466. 294. 1993 Peters, J. M., Wiley, L. M., Zidenberg-Cherr, S., and Keen, C. L. Influence of periconceptional zinc deficiency on embryonic plasma membrane function in mice. Teratogenesis, Carcinogenesis, and Mutagenesis 13:15-21. 295. 1993 Cha, S., Leung, P., Taubeneck, M. W., Keen, C. L., Gershwin, M. E., Gupta, R. S., and Fletcher, M. P. Effects of zinc deprivation on heat shock protein (HSP)-65 and -70 gene expression in pregnant rats. Nutrition Research 13: 1077-1086. 296. 1993 Sánchez, D. J., Domingo, J. L., Llobet, J. M., and Keen, C. L. Maternal and developmental toxicity of manganese in the mouse. Toxicology Letters 69: 45-52. 297. 1993 Oster, M. H., Llobet, J. M., Domingo, J. L., German, J. B., and Keen, C. L. Vanadium treatment of diabetic Sprague-Dawley rats results in tissue vanadium accumulation and pro-oxidant effects. Toxicology 83: 115-130. 298. 1993 Keen, C. L., Bendich, A., and Willhite, C. C. Maternal Nutrition and Pregnancy Outcome. Annals of the New York Academy of Sciences, Vol. 678, 372 pp. 299. 1993 Davis, P. A., Platon, J-F., Gershwin, M. E., Halpern, G. M., Keen, C. L., DiPaolo, D., Alexander, J. and Ziboh, V. A. A linoleate-enriched cheese product reduces low-density lipoprotein in moderately hypercholesterolemic adults. Annals of Internal Medicine 119: 555-559. 300. 1994 Keen, C. L. and Zidenberg-Cherr, S. Manganese toxicity in humans and experimental animals. In: Manganese in Health and Disease (D. Klimis-Tavantzis, ed.), CRC Press, Boca Raton, FL, pp. 193-205. 301. 1994 Baly, D. L., Walter, R. M., and Keen, C. L.
Manganese metabolism and diabetes. In: Manganese in Health and Disease
(D. Klimis-Tavantzis, ed.), CRC Press, Boca Raton, FL, pp. 101-113. 303. 1994 King, J. C. and Keen, C. L. Zinc. In: Modern Nutrition in Health and Disease, 8th edition (M. E. Shils, J. A. Olson and M. Shike, eds.), Lea & Febiger, Philadelphia, pp. 214-230. 304. 1994 Graham, T. W., Thurmond, M. C., Mohr, F. C., Holmberg, C. A., Anderson, M., and Keen, C. L. Relationships between maternal and fetal liver copper, iron, manganese and zinc concentrations and fetal developments in California holstein dairy cows. Journal of Veterinary Diagnostic Investigation 6: 77-87. 305. 1994 Keen, C. L. and Zidenberg-Cherr, S. Should vitamin-mineral supplements be recommended for all women with childbearing potential? American Journal of Clinical Nutrition 59: 532S-539S. 306. 1994 Domingo, J. L., Gomez, M., Sanchez, D. J., Llobet, J. M., Corbella, J., and Keen, C. L. Normalization of hyperglycemia by vanadate on vandyl treatment in diabetic rats: pharmacological and toxicological aspects. Trace Elements and Electrolytes 11: 16-22 307. 1994 Taubeneck, M. W., Datson, G. P., Rogers, J. M., and Keen, C. L. Altered maternal zinc metabolism following exposure to diverse developmental toxicants. Reproductive Toxicology 8: 25-40. 308. 1994 Olin, K. L., Walter, R. M., and Keen, C. L. Copper deficiency affects seleno-glutathione peroxidase and selenodeiodinase activities and antioxidant defense in weanling rats. American Journal of Clinical Nutrition 59: 654-658. 309. 1994 Rucker, R. B., Lonnerdal, B., and Keen, C. L. Intestinal absorption of nutritionally important trace elements. In: Physiology of the Gastrointestinal Tract (L.R. Johnson, ed.), Raven Press, New York, NY, pp. 2183-2202. 310. 1994 Daston, G. P., Overmann, G. J., Baines, D., Taubeneck, M. W., Lehman-McKeeman, L. D., Rogers, J. M., and Keen, C. L. Altered Zn status by alpha-hederin in the pregnant rat and its relationship to adverse developmental outcome. Reproductive Toxicology 8: 15-24. 311. 1994 Tamura, T., Freeberg, L. E., Johnston, K. E., and Keen, C. L. In vitro zinc stimulation of angiotensin-converting enzyme activities in various tissues of zinc-deficient rats. Nutrition Research 6:919-928. 312. 1994 Golub, M. S., Takeuchi, P. T., Keen, C. L., Gershwin, M. E., Hendrickx, A. G., and Lonnerdal, B. Modulation of behavioral performance of prepubertal monkeys by moderate dietary zinc deprivation. American Journal of Clinical Nutrition 60:238-243. 313. 1994 Golub, M. S., Han, B., Keen, C. L., and Gershwin, M. E. Auditory startle in Swiss Webster mice fed excess aluminum in diet. Neurotoxicology and Teratology 16:423-425. 314. 1994 Gospe, S. M., Olin, K. L., and Keen, C. L. Reduced GABA synthesis in pyridoxine-dependent seizures. The Lancet 343:1133-1134. 315. 1994 Olin, K. L., Stearns, D. M., Armstrong, W. H., and Keen, C. L. Comparative retention/absorption of 51chromium (51Cr) from 51Cr chloride, 51Cr nicotinate and 51Cr picolinate in a rat model. Trace Elements and Electrolytes 11: 182-186. 316. 1994 Keen, C. L., Zidenberg-Cherr, S., and Lonnerdal,
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Olin, eds.). ILSI Press, Washington, DC., pp. 221-235. 318. 1994 Oster, M. H., Uriu-Hare, J. Y., Trapp, C. L., Stern, J. S., and Keen, C. L. Dietary macronutrient composition influences tissue trace element accumulation in diabetic Sprague-Dawley rats. Proceedings of the Society for Experimental Biology and Medicine 207:67-75. 319. 1994 Bui, L. M., Keen, C. L., and Dubick, M. A. Influence of 12-week nicotine treatment and dietary copper on blood pressure and indices of the antioxidant system in male spontaneous hypertensive rats. Biological Trace Element Research 46:67-78. 320. 1994 Graham, T. W., Thurmond, M. C., Gershwin, M. E., Picanso, J. P., Garvey, J. S., and Keen, C. L. Serum zinc and copper concentrations in relation to spontaneous abortion in cows: implications for human fetal loss. Journal of Reproduction and Fertility 102:253-262. 321. 1994 Cohen, S. M., Olin, K. L., Fever, W. J., Hjelmeland, L., Keen, C. L., and Morse, L. S. Low glutathione reductase and peroxidase activity in age-related macular degeneration. British Journal of Ophthalmology 78:791-794. 322. 1994 Domingo, J.L., Gomez, M., Sanchez, D.J., Llobet, J.M., and Keen, C.L. Relationship between reduction in food intake and amelioration of hyperglycemia by oral vanadate in STZ-induced diabetic rats. (Letter) Diabetes 43:1267. 323. 1994 Buchman, A.L., Keen, C.L., Vinters, H.V., Harris, E., Chugani, H.T., Bateman, B., Rodgerson, D., Vargas, J., Verity, A., and Ament, M. Copper deficiency secondary to a copper transport defect: A new copper metabolic disturbance. Metabolism 43:1462-1469. 324. 1994 Keen CL and Zidenberg-Cherr S. Trace element and vitamin interactions in free radical defense. In: Nutrition in a Sustainable Environment. (Wahlquist ML, Truswell AS, Smith R, Nestle P, eds.) Smith-Gordon, London, pp. 799-803. 325. 1995 Olin, K. L., Morse, L. S., Murphy, C., Paul-Murphy, J., Line, S., Bellhorn, R. W., Hjelmeland, L. M., and Keen, C. L. Trace element status and free radical defense in elderly rhesus macaques (Macaca mulatta) with Macular Drusen. Proceedings of the Society for Experimental Biology and Medicine 208:370-377. 326. 1995 Bui, L. M., Keen, C. L., and Dubick, M. A. Comparative effects of 6-week nicotine treatment on blood pressure and components of the antioxidant system in male spontaneously hypertensive (SHR) and normotensive Wistar Kyoto (WKY) rats. Toxicology 98:57-65. 327. 1995 Oteiza, P.I., Olin, K. L., Fraga, C. G., and Keen, C. L. Zinc deficiency causes oxidative damage to proteins, lipids and DNA in rat testes. The Journal of Nutrition 125:823-829. 328. 1995 Peters, J. M., Duncan, J. R., Wiley, L. M., and Keen, C. L. Infuence of antioxidants on cadmium toxicity of mouse preimplantation embryos in vitro. Toxicology 99:11-18. 329. 1995 Liao, Z., Allred, J., Keen, C. L., McCune, S. A., Rucker, R. B., and Medeiros, D. M. Copper deficiency alters isomyosin types and levels of laminin, fibronectin and cytochrome c oxidase subunits from rat hearts. Comparative Biochemistry and Physiology 111B:61-67. 330. 1995 Peters, J. M., Wiley, L. M., Zidenberg-Cherr, S., and Keen, C. L. Periconceptional zinc deficiency affects uterine 3H-estradiol binding in mice. Teratogenesis, Carcinogenesis, and Mutagenesis 15:23-31. 331. 1995 Peters, J. M., Duncan, J. R., Wiley, L. M., Rucker, R. B., and Keen, C. L. Effect of a metallothionein antisense oligonucleotide on embryo development. Reproductive Toxicology 9:123-130. 332. 1995 Taubeneck, M. W., Daston, G. P., Rogers, J. M., Gershwin, M. E., Ansari, A., and Keen, C. L. Tumor necrosis factor- alters maternal and embryonic zinc metabolism and is developmentally toxic in mice. The Journal of Nutrition 125:908-919. 333. 1995 Sakanashi, T. M., Keen, C. L., Hong, K. H., Gershwin, M. E., and Fletcher, M. P. Alterations in the chemotactic and respiratory burst responses of peripheral blood neutrophils from zinc deficient rats. The Journal of Nutritional Immunology 3:3-18. 334. 1995 Olin, K.L., Golub, M.S., Gershwin, M.E., Hendricks, A.G., Lonnerdal, B., and Keen, C.L. Extracellular superoxide dismutase activity is affected by dietary zinc intake in nonhuman primate and rodent models. American Journal of Clinical Nutrition 61:1263-1267. 335. 1995 Jankowski, M.A., Uriu-Hare, J.Y., Rucker, R.B., Rogers, J.M., and Keen, C.L. Maternal zinc deficiency, but not copper deficiency or diabetes, results in increased embryonic cell death in the rat: Implications for mechanisms underlying abnormal development. Teratology 51:85-93. 336. 1995 Golub, M.S., Han, B., Keen, C.L., Gershwin, M.E., and Tarara, R.P. Behavioral performance of Swiss Webester mice exposed to excess dietary aluminum during development or during development and as adults. Toxicology and Applied Pharmacology 133:64-72 337. 1995 Graham, T.W., Giri, S.N., Daels, P.F., Cullor, J.S., Keen, C.L., Thurmond, M.C., Dellinger, J.D., Stabenfeldt, G.H., and Osburn, B.I. Associations among prostaglandin F2 , plasma zinc, copper and iron concentrations and fetal loss in cows and mares. Theriogenology 44:379-390.
339. 1995 Keen, C.L. Cytokine Nutrition and Cancer. In: Nutrition and Cancer (P. Sachet, M. Boiron, and G. Halpern, eds.). Cerin Symposium. Cerin, Paris, France, pp. 209-229 340. 1995 Clegg, M.S., Keen, C.L., and Donovan, S.M. Zinc deficiency influences the distribution of serum insulin-like growth factor binding proteins in the rat. Metabolism 44:1495-1501. 341. 1995 Uriu-Hare, J.Y., Swan, S.H., Bui, L.M., Neutra, R.R., and Keen, C.L. Drinking water source and reproductive outcomes in Sprague-Dawley rats. Reproductive Toxicology 9:549-561. 342. 1995 Domingo, J.L., Gomez, M., Sanchez, D., Llobet, J.M., and Keen, C.L. Toxicology of vanadium compounds in diabetic rats: The action of chelating agents on vanadium accumulation. Molecular and Cellular Biochemistry. 153: 233-240. 343. 1995 Keen, C.L., and Lonnerdal, B. Toxicity of essential and beneficial metabolism. Manganese. In: Handbook on Metal Ligand Interactions in Biological Fluids (Berthon, G., Editors), Marcel Dekker Publishing Co., New York, 2:683-688. 344 1995 Rogers JM, Taubeneck MW, Daston GP, Sulik KK, Zucker RM, Elstein KH, Jankowski MA, and Keen CL. Zinc deficiency causes apoptosis but not cell cycle alterations in organogenesis-stage rat embryos: Effect of varying duration of deficiency. Teratology 52:149-159. 345. 1995 Keen CL, Taubeneck MW, Daston GP, Gershwin ME, Ansari A and Rogers JM. Primary and secondary zinc deficiency as factors contributing to abnormal central nervous system development. Developmental Brain Dysfunction 8:79-89. 346. 1996 Rucker, R.B., Romero-Chapman, N., Wong, T., Lee, J. Steinberg, F.M., McGee, C., Clegg, M.S., Reiser, K., Kosonen, T., Uriu-Hare, J.Y., Murphy, J., and Keen, C.L. Modulation of lysyl oxidase by dietary copper in rats. The Journal of Nutrition. 126:51-60. 347. 1996 Dodman, N.H., Knowles, K.E., Shuster, L., Moonfanelli, A.A., Tidwell, A.S., andKeen, C.L. Behavioral changes associated with suspected complex partial seizures in Bull Terriers. Journal of the American Veterinary Medical Association. 208:688-691. 348. 1996 Smith, G.C., Clegg, M.S., Keen, C.L., and Grivetti, L.E. Mineral values of selected plant foods common to Southern Burkina Faso and Niamey, Niger, West Africa. The International Journal of Food Sciences and Nutrition 47:41-53. 349. 1996 Golub, M.S., Han, B., and Keen, C.L. Iron and manganese uptake by offspring of lactating mice fed a high aluminum diet. Toxicology. 109:111-118. 350. 1996 Golub, M.S., Han, B., and Keen, C.L. Aluminum alters iron and manganese uptake and regulation of surface transferrin receptors in primary rat oligodendrocyte cultures. Brain Research. 719:72-77. 351. 1996 Keen, C.L., and Zidenberg-Cherr, S. Manganese. In: Present Knowledge in Nutrition, Seventh Edition. (E.E. Ziegler and L.J. Filer, Jr., Editors.), ILSI Press, Washington, D.C., 33:334-343. 352. 1996 Olin, K.L., Cherr, G.N., Rifkin, E., and Keen, C.L. The effects of some redox-active metals and reactive aldehydes on DNA-protein cross-links in vitro. Toxicology. 110:1-8. 353. 1996 Miller, G.D., Keen, C.L., Stern, J.S., and Uriu-Hare, J.Y. Copper absorption, endogenous excretion and distribution in Sprague-Dawley and lean (FaFa) Zucker rats. Biological Trace Element Research 53:261-279. 354. 1996 Keen, C.L. Teratogenic effects of essential trace metals: deficiencies and excesses. In: Toxicology of Metals. (Chang, L.W., Magos, L., Suzuki, T., eds.) CRC Press, New York, pp. 977-1001. 355. 1996 Golub, M.S., Keen, C.L., Gershwin, M.E., Styne, D.M., Takeuchi, P.T., Ontell, F., Walter, R.M., and Hendrickx, A.G. Adolescent growth and maturation in zinc-deprived rhesus monkeys. American Journal of Clinical Nutrition 64:274-85-91. 356. 1996 Oteiza, P.I., Olin, K.L., Fraga, C.G., and Keen, C.L. Oxidant defense systems in testes from zinc deficient rats. Proceedings of the Society of Experimental Biology and Medicine 213:85-91. 357. 1996 Fu, S.S., Sakanashi, T.M., Rogers, J.M., Hong, K.H., and Keen, C.L. Influence of dietary folic acid on the developmental toxicity of methanol and the frequency of chromosomal breakage in the CD-1 mouse. Reproductive Toxicology 10:455-463. 358. 1996 Sakanashi, T.M., Rogers, J.M., Fu, S.S., Connelly, L.E., and Keen, C.L. Influence of maternal folate status on the developmental toxicity of methanol in the CD-1 mouse. Teratology 54:198-206. 359. 1996 Golub, M.S., Takeuchi, P.T., Keen, C.L., Hendrickx, A.G., and Gershwin, M.E. Activity and attention in zinc-deprived adolescent monkeys. American Journal of Clinical Nutrition 64:908-915. 360. 1996 Golub, M.S., Han, B., and Keen, C.L. Developmental patterns of aluminum and five essential mineral elements in the central nervous system of the fetal and infant guinea pig. Biological Trace Element Research. 55: 241-251. 361. 1997 Turnlund, J.R., Scott, K.C., Peiffer, G.L., Jang, A.M., Keyes, W.R., Keen, C.L., and Sakanashi, T.M. Copper status of young men consuming a low-copper diet. American Journal of Clinical Nutrition. 65:72-8. 362. 1997 Hanna, L.A., Peters, J.M., Wiley, L.M., Clegg, M.S., and Keen, C.L. Comparative effects and nonessential metals on preimplantation mouse embryo development in vitro. Toxicology 116:123-31. 363. 1997 Uchida, Y., Moon-Fanelli, A.A., Dodman, N.H., Clegg, M.S., and Keen, C.L. Serum concentrations of zinc and copper in Bull Terriers with lethal acrodermatitis and tail-chasing behavior. American Journal of Veterinary Research 58:808-810. 364. 1997 Aldrian, P.S., Keen, C.L., Lönnerdal, B. and Dewey, K.G. Effects of coffee consumption on iron, zinc and copper status in nonpregnant and pregnant Sprague-Dawley rats. The International Journal of Food Sciences and Nutrition 48:177-189. 365. 1997 Dubick, M.A. and Keen, C.L. Effects of acetaldehyde administration on tissue trace elements and superoxide dismutase activity in rats. Environmental and Nutritional interactions 1:161-169. 366. 1997 Verstraetten, S.V., Golub M.S, Keen, C.L. and Oteiza, P.I. Myelin is a preferential target of aluminum-mediated oxidative damage. Archives of Biochemistry and Biophysics 344:289-94. 367. 1997 Kosonen, T., Uriu-Hare, J.Y., Clegg, M.S., Keen, C.L. and Rucker, R.B. Incorporation of copper into lysyl oxidase. Biochemistry Journal 327:283-289. 368. 1997 Peters JM, Taubeneck MW, Keen CL, and Gonzalez FJ. Di(2-ethylhexyl) phthalate induces a functional zinc deficiency during pregnancy and teratogenesis that are independent of peroxisome proliferator-activated receptor-a. 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